Air distance from Santo Domingo, Dominican Republic to Madrid, Spain is 4164.5 Miles (6702.1 Kilometers / 3616.4 Nautical Miles).
8 hrs, 38 mins is the flight duration between Santo Domingo and Madrid. This is the In-The-Air flight time. You should also add the taxi time, airport wait times and possible delays due to bad weather, etc. for the total flight duration time.